I have noticed crews of sagebrush seed harvesters along the highway south of our town in the fall. They harvest in an area where the sagebrush seem to be especially large and bushy.
They have large cloth bags which they hold the seed heads over and then beat on the heads with tennis rackets. Towards the end of the day their pickup trucks are piled high with these bags that resemble giant pillows. I don't know how they separate the chaff from the seed.
There was a huge fire (90,000 acres) in the hills and mountains near our town this past summer. Much of the burned area is now being seeded with a mixture of sagebrush, bitterbrush, and other native plants. This is important winter range for Mule Deer and they are going to be in trouble, especially if it is a harsh winter.