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local anesthetic resistance for folks who have been stung by scorpions

Posts: 142
Location: Sonoran Desert, USA
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I think this is the correct forum for this, but let me know if not, please.

I was just reminded about this issue from another post on venomous animals and thought I'd share, for those who are not aware, because for anyone who is making survival plans that involve access to local anesthetic for pain relief during a disaster, this could impact your strategy for pain management, potentially.

To sum it up: "scorpion venom is known to affect the pumping mechanism of sodium channels in the nerve fibres, which are involved in the mechanism of action of local anaesthetic drugs, it may be responsible for the development of ‘resistance’ to the action of local anaesthetic agents." (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3546248/?report=printable )

In anesthetics injected into the spinal column, numerous scorpion stings seem to be able to sometimes create a complete resistance to the injected anesthetic in the patient. Even one scorpion stings may create a delayed time to the body responding to the anesthetic, or a resistance to it (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3748676/?report=printable). Obviously, this isn't exactly something we'd be doing in a survival situation.

However, there have also been cases of it impacting injected local anesthetics in other areas, like for dental work (https://www.arcjournals.org/pdfs/aja/v2-i2/3.pdf ).

General and topical anesthetics and analgesics don't seem to be impacted by the scorpion stings, at least based on the fact that they seemed to have worked on those who had a failed spinal block due to previous scorpion stings. At least, I haven't seen any research indicating a problem.

But for anyone who has been stung by scorpions in the past, it might be worthwhile to have extra pain relief options if you had been planning on using some local anesthetics in survival situations (or for situations where you would normally expect to use local anesthetics), just in case.  

I'm keeping my eye on the research periodically for personal reasons (my kid has been stung by scorpions and a lot of anesthetics don't seem to do much for them at all - the reason we found out about this in the first place), and if I ever find any new updated information, I'll make sure to put it up here.
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Location: Gulf of Mexico cajun zone 8
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Very interesting. There was one time when my dentist couldn't get a tooth numb enough. Four or five shots of Novacaine, or whatever local anesthetic he used. I've been stung too many times but don't recall how recently prior to that experience. My entire face was completely numb for many hours but the tooth never got numb enough. It took all night for my face to get back to normal.
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